cover image MAKING SENSE OF LIFE: Explaining Biological Development with Models, Metaphors, and Machines

MAKING SENSE OF LIFE: Explaining Biological Development with Models, Metaphors, and Machines

Evelyn Fox Keller, . . Harvard Univ., $29.95 (352pp) ISBN 978-0-674-00746-8

Keller (The Century of the Gene), professor of history and philosophy of science at MIT, analyzes the history of developmental biology. She explains the type of information scientists have accepted, why changes in acceptance may occur and, on a broader scale, what it means to understand the natural world. Models we now view as scientifically absurd held sway a mere century ago, while others, based on mathematics and visualized on computers but devoid of any confirmation from a biology laboratory, have now captured many imaginations. Keller shows that biology, like all of the sciences, is influenced by many factors: "Both what counts as knowledge and what we mean by knowing depend on the kinds of data we are able to acquire, on the ways in which those data are gathered, and on the forms in which they are represented." While Keller's prose is graceful and informed, her thesis is complex and unlikely to be fully appreciated by those without significant grounding in philosophy and biology. (Mar.)