| 1 | The Secret. Rhonda Byrne. Atria/Beyond Words, $23.95 ISBN 978-15827-0170-7 | 1 | 59 |
| 2 | Women & Money. Suze Orman. Spiegel & Grau, $24.95 ISBN 978-0-385-51931-1 | – | 10 |
| 3 | In Defense of Food. Michael Pollan. Penguin Press, $21.95 ISBN 978-1-5942-0145-5 | 3 | 7 |
| 4 | You: Staying Young. Michael F. Roizen, M.D., & Mehmet C. Oz, M.D. Free Press, $26 ISBN 978-0-7432-9256-6 | 2 | 16 |
| 5 | Become a Better You. Joel Osteen. Free Press, $25 ISBN 978-0-7432-9688-5 | 4 | 18 |
| 6 | Does This Clutter Make My Butt Look Fat? Peter Walsh. Free Press, $25 ISBN 978-1-416-56016-6 | 6 | 2 |
| 7 | I Am America (and So Can You!). Stephen Colbert. Grand Central, $26.99 ISBN 978-0-446-58050-2 | 8 | 19 |
| 8 | Reconciliation. Benazir Bhutto. Harper, $27.95 ISBN 978-0-06-156758-2 | – | 1 |
| 9 | Real Change. Newt Gingrich. Regnery, $27.95 ISBN 978-1-5969-8053-2 | 7 | 5 |
| 10 | How Not to Look Old. Charla Krupp. Springboard Press, $25.99 ISBN 978-0-446-58114-1 | 5 | 6 |
| 11 | An Inconvenient Book. Glenn Beck. Threshold Editions, $26 ISBN 978-1-416-55219-2 | 9 | 13 |
| 12 | The Dangerous Book for Boys. Conn & Hal Iggulden. Collins, $24.95 ISBN 978-0-06-124358-5 | 11 | 39 |
| 13 | The Age of American Unreason. Susan Jacoby. Pantheon, $26 ISBN 978-0-375-42374-1 | – | 1 |
| 14 | The Daring Book for Girls. Andrea J. Buchanan & Miriam Peskowitz. Collins, $24.95 ISBN 978-0-06-147257-2 | 15 | 16 |
| 15 | Deceptively Delicious. Jessica Seinfeld. Collins, $24.95 ISBN 978-0-06-125134-4 | 10 | 19 |