| 1 | The Last Lecture. Randy Pausch with Jeffrey Zaslow. Hyperion, $21.95 ISBN 978-1-4013-2325-7 | 1 | 2 |
| 2 | Just Who Will You Be? Maria Shriver. Hyperion, $14.95 ISBN 978-1-4013-2318-9 | – | 1 |
| 3 | The Secret. Rhonda Byrne. Atria/Beyond Words, $23.95 ISBN 978-15827-0170-7 | 2 | 68 |
| 4 | Mistaken Identity. Don & Susie Van Ryn and Newell, Colleen & Whitney Cerak. Howard Books, $21.99 ISBN 978-1-4165-6735-6 | 3 | 4 |
| 5 | Beautiful Boy. David Sheff. Houghton Mifflin, $24 ISBN 978-0-618-68335-2 | 6 | 8 |
| 6 | Home. Julie Andrews. Hyperion, $26.95 ISBN 978-0-7868-6565-9 | 4 | 3 |
| 7 | Ladies of Liberty. Cokie Roberts. Morrow, $26.95 ISBN 978-0-06-078234-4 | 5 | 2 |
| 8 | Escape. Carolyn Jessop with Laura Palmer. Broadway, $24.95 ISBN 978-0-7679-2756-7 | 9 | 2 |
| 9 | Bad Money. Kevin Phillips. Viking, $25.95 ISBN 978-0-670-01907-6 | – | 1 |
| 10 | Georgia Cooking in an Oklahoma Kitchen. Trisha Yearwood. Clarkson Potter, $29.95 ISBN 978-0-307-38137-8 | 10 | 2 |
| 11 | Women & Money. Suze Orman. Spiegel & Grau, $24.95 ISBN 978-0-385-51931-1 | 7 | 19 |
| 12 | Become a Better You. Joel Osteen. Free Press, $25 ISBN 978-0-7432-9688-5 | 8 | 27 |
| 13 | Girls Like Us. Sheila Weller. Atria, $27.95 ISBN 978-0-7434-9147-1 | 12 | 2 |
| 14 | In Defense of Food. Michael Pollan. Penguin Press, $21.95 ISBN 978-1-5942-0145-5 | – | 15 |
| 15 | Armageddon in Retrospect. Kurt Vonnegut. Putnam, $24.95 ISBN 978-0-399-15508-6 | 13 | 3 |
