| 1 | The Last Lecture. Randy Pausch with Jeffrey Zaslow. Hyperion, $21.95 ISBN 978-1-4013-2325-7 | 1 | 25 |
| 2 | Hot, Flat, and Crowded. Thomas L. Friedman. Farrar, Straus & Giroux, $27.95 ISBN 978-0-374-16685-4 | 2 | 3 |
| 3 | A Bold Fresh Piece of Humanity. Bill O'Reilly. Broadway, $26 ISBN 978-0-7679-2882-3 | – | 1 |
| 4 | Before You Do. T.D. Jakes. Atria, $25 ISBN 978-1-416-54728-0 | – | 1 |
| 5 | Breakthrough. Suzanne Somers. Crown, $25.95 ISBN 978-1-4000-5327-8 | 4 | 3 |
| 6 | The War Within. Bob Woodward. Simon & Schuster, $32 ISBN 978-1-416-55897-2 | 3 | 3 |
| 7 | Pieces of My Heart. Robert J. Wagner with Scott Eyman. Morrow, $25.95 ISBN 978-0-06-137331-2 | – | 1 |
| 8 | Guinness World Records 2009. Guiness Publishing, $28.95 ISBN 978-1-904994-37-4 | 9 | 2 |
| 9 | The Secret. Rhonda Byrne. Atria/Beyond Words, $23.95 ISBN 978-15827-0170-7 | 5 | 91 |
| 10 | Dewey. Vicki Myron with Bret Witter. Grand Central, $19.99 ISBN 978-0-446-40741-0 | – | 1 |
| 11 | Stori Telling. Tori Spelling. Simon Spotlight Entertainment, $24.95 ISBN 978-1-416-95073-8 | 6 | 17 |
| 12 | Are You There, Vodka? It's Me, Chelsea. Chelsea Handler. Simon Spotlight Entertainment, $24.95 ISBN 978-1-416-95412-5 | 11 | 23 |
| 13 | Mother Warriors. Jenny McCarthy. Dutton, $24.95 ISBN 978-0-525-95069-1 | – | 1 |
| 14 | Real Life. Dr. Phil McGraw. Free Press, $26.99 ISBN 978-0-7432-6495-2 | 7 | 2 |
| 15 | Through the Storm. Lynne Spears with Lorilee Craker. Thomas Nelson, $24.99 ISBN 978-1-5955-5156-6 | 8 | 2 |
